Over the last two decades, e-waste has become a crisis, receiving significant attention from activist, environmental groups, policymakers, news media, and academics. E-waste processing hubs in Africa and Asia pejoratively labelled “digital dumps” are at the center of the so-called crisis. This dissertation is about Agbogbloshie, a site in Accra, the capital of Ghana, ostensibly “the world’s largest e-waste dump.” I examine the making of this iconic imaginary of Agbogbloshie, the grounds on which it is built, and the effects of its circulation. Broadly, I investigate the knowledge-making practices central to representations of Agbogbloshie as “problem space” in need of interventions. I explore how advocacy groups, institutions (academic scholars), and individuals frame the content and relevance of knowledge about the site to elicit certain forms of interventions and how within this context, the knowledge they produce itself becomes a site of struggle around which contentious politics take place. I demonstrate that although the intention is to make visible the environmental and health effects of e-waste processing, the imaginaries produced about Agbogbloshie within ewaste science and advocacy do certain kinds of harm. Imaginaries of Agbogbloshie such as it is “the world’s largest e-waste dump” are not just representations; they do work, including adding to the harms experienced by those who live and work at the site. Questioning imaginaries of e-waste at Agbogbloshie, I open spaces where the tensions of Agbogbloshie as a site of/for e-waste science and advocacy can be more carefully thought through and done differently.