People everywhere are bombarded with claims about what might improve or harm their health. To make well-informed healthcare choices, they must be able to assess the reliability of those claims. We have developed the Informed Health Choices (IHC) primary school resources to help enable them to do this. These resources include this guide for teachers, a book for children1 and an exercise book. The book for children includes a comic, exercises and instructions for classroom activities. It is written for children who are 10 years old or older. These resources are the first in a series of learning resources to enable people to assess the reliability of claims and to make well-informed healthcare choices. We have developed these resources from 2014 to 2016 through a human-centred design approach. This entails involving target users in the design process as co-creators in multiple cycles of prototyping, user testing and piloting. We tested the resources in Uganda, Kenya, Rwanda and Norway. Feedback shows that children and teachers perceive these resources to be useful.