The copper-cobalt outcrops of Upper Katanga and north-western Zambia host a particular flora which comprises an estimated 750 species of which more than 400 are treated in this copper-cobalt field guide. The aim of Copper-Cobalt Flora of Upper Katanga and Copperbelt, resulting from several years of intensive field work and study, is to bring together the basic knowledges permitting an easy approach to the identification of a great number of the species to be encountered. More than 400 species are illustrated with color photographs and/or drawings together with comments concerning synonyms, habit, description, ecology and distribution. Plant species are listed and colour-coded according to classification: Cyanoprocaryota, lichenized Fungi, Anthocerophyta, Marchantiophyta and Bryophyta (red edge), Lycophyta and Monilophyta (green edge), Magnoliopsida (blue edge) and Liliopsida (yellow edge). An index allows easy location either according to genus and species. An account of the research on copper-cobalt ecosystems carried out during the last ten years in southeastern D.R. Congo is also presented. The editors have spent more than twenty years in the area concerned and have collected more than 8,500 voucher specimens, including eleven species new to science (holotypes). The aim of the present Guide is to offer a valuable support for easy field identification of a large number of plant species observed on the copper-cobalt deposits of Upper Katanga and the Copperbelt. We hope it will make it easy for scientists and laymen alike to identify a large number of plants in the field, the Katangan copper flora being still imperfectly known. Several sites have never been explored from a botanical point of view, whilst others need further visits during the diverse seasons that occur in the area of concern. At least some 170 copper sites have been recognized.